Rare Bradenton Opportunity - 5 Bedrooms, 3,422 SF, Nearly ½ Acre & Endless Possibilities! 5423 21st St W, Bradenton, FL 34207 is the kind of property that checks nearly every box including space, flexibility, location, investment potential, and peace of mind. With 3,422 square feet under air, 5 bedrooms, and a lot measuring almost half an acre, this is an exceptionally versatile property that can serve as a spacious single-family residence, a duplex, or a unique triplex-style investment. In fact, at the time of listing, this is the only 5-bedroom home in Manatee County offering more than 3,000 square feet of living space making this a truly distinctive opportunity. The home's flexible design allows each section to function independently while remaining connected. Interior areas can be closed off, creating privacy and separation for extended family, rental income, guests, or an owner-occupant looking to maximize the property's potential. The left-side unit features 2 bedrooms and 1 bath, along with an inviting open-concept kitchen and dining area. It's ideal for comfortable everyday living. Upstairs, you'll find a remarkably spacious open-concept kitchen, family, and gathering room, plus 1 bedroom and 1 bath. With its own entrance, this space is perfectly suited for an in-home business, private guest quarters, multigenerational living, or additional rental potential. The right-side unit offers 1 bedroom and 2 baths, with an open kitchen/family-room layout and the added benefit of its own private backyard. And for the big-ticket items, the property offers valuable updates with a 2021 roof and 2019 HVAC system. Whether you're searching for a large primary residence, a multigenerational home, a property with rental income potential, or a unique investment opportunity, this one delivers flexibility that is difficult to find in today's market. Location puts you close to everything that makes Bradenton so desirable, with convenient access to Gulf Coast beaches, Sarasota-Bradenton International Airport, downtown Bradenton, the Manatee River, shopping, dining, entertainment, and major roadways connecting you throughout the greater Sarasota-Bradenton area. One property. Multiple possibilities. Nearly half an acre. Over 3,400 square feet. Five bedrooms. And a location that puts the best of Bradenton within reach. Come see why 5423 21st St W isn't just a home. it's an opportunity!